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KMID : 0895419930030020188
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Journal of Korean Society of Occupational and Enviromental Hygiene
1993 Volume.3 No. 2 p.188 ~ p.193
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Blood Toluene and Urine Hippuric Acid Concentrations of Occupationally Toluene - exposed Workers
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조영숙/Cho, Young Sook
김기웅/양정선/이종성/강성규/정호근/Kim, Ki Woong/Yang, Jung Sun/Lee, Jong Sung/Kang, Seong Kyu/Chung, Ho Keun
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Abstract
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Toluene in air and blood and hippuric acid in urine were checked for the 41 female workers who are exposed to toluene and have normal liver function in shoe making factories in July, 1993. Toluene in air was sampled with charcoal by personal air sampler at least 4 times and analyzed by gas chromatography. At the end of shift, blood and spot urine were collected with a vacuum tube containing EDTA and a polyethylene bottle for detecting blood toluene and urine hippuric acid and analyzed by gas chromatography and high performance liquid chromatography.
Means of air and blood toluene and urine hippuric acid concentrations were 34.35ppm, 0.360㎎/L, and 1.78g/g creatinine, respectively.
Toluene in air showed a good correlation with hippuric acid in urine(r=0.4503) and toluene in blood(r=0.4596). The hippuric acid in urine and toluene in blood corresponded to exposure of 100ppm toluene in air were 2.628g/g creatinine and 0.481㎎/L.
Blood toluene and urine hippuric acid expected ratio were not correlated to the obesity index and working duration, however increased with age.
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